Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain

During viral replication, herpesviruses package their DNA into the procapsid by means of the terminase protein complex. In human cytomegalovirus (herpesvirus 5), the terminase is composed of subunits UL89 and UL56. UL89 cleaves the long DNA concatemers into unit-length genomes of appropriate length...

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Detalles Bibliográficos
Autores principales: Nadal, Marta, Mas, Philippe J., Blanco, Alexandre G., Arnan, Carme, Solà, Maria, Hart, Darren J., Coll, Miquel
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941324/
https://ncbi.nlm.nih.gov/pubmed/20805464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007144107
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