CCAAT/enhancer binding protein delta (C/EBPδ, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage

Maintenance of genomic integrity is an essential cellular function. We previously reported that the transcription factor and tumor suppressor CCAAT/enhancer binding protein δ (C/EBPδ, CEBPD; also known as “NFIL-6β”) promotes genomic stability. However, the molecular mechanism was not known. Here, we...

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Autores principales: Wang, Jun, Sarkar, Tapasree Roy, Zhou, Ming, Sharan, Shikha, Ritt, Daniel A., Veenstra, Timothy D., Morrison, Deborah K., Huang, A-Mei, Sterneck, Esta
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941265/
https://ncbi.nlm.nih.gov/pubmed/20805509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002603107
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