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CCAAT/enhancer binding protein delta (C/EBPδ, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage

Maintenance of genomic integrity is an essential cellular function. We previously reported that the transcription factor and tumor suppressor CCAAT/enhancer binding protein δ (C/EBPδ, CEBPD; also known as “NFIL-6β”) promotes genomic stability. However, the molecular mechanism was not known. Here, we...

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Detalhes bibliográficos
Main Authors: Wang, Jun, Sarkar, Tapasree Roy, Zhou, Ming, Sharan, Shikha, Ritt, Daniel A., Veenstra, Timothy D., Morrison, Deborah K., Huang, A-Mei, Sterneck, Esta
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941265/
https://ncbi.nlm.nih.gov/pubmed/20805509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002603107
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