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Peptide Arrays Identify Isoform-Selective Substrates for Profiling Endogenous Lysine Deacetylase Activity

[Image: see text] This paper reports the development of a class of isoform-selective peptide substrates for measuring endogenous lysine deacetylase (KDAC) activities in cell culture. The peptides were first identified by comparing the substrate specificity profiles of the four KDAC isoforms KDAC2, K...

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Auteurs principaux: Gurard-Levin, Zachary A., Kilian, Kristopher A., Kim, Joohoon, Bähr, Katinka, Mrksich, Milan
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2010
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941244/
https://ncbi.nlm.nih.gov/pubmed/20849068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100088g
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