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Profiling the selectivity of DNA ligases in an array format with mass spectrometry
This article describes a method for the global profiling of the substrate specificities of DNA ligases and illustrates examples using the Taq and T4 DNA ligases. The method combines oligonucleotide arrays, which offer the benefits of high throughput and multiplexed assays, with mass spectrometry to...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2800213/ https://ncbi.nlm.nih.gov/pubmed/19854942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp827 |
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