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Combining Mass Spectrometry and Peptide Arrays to Profile the Specificities of the Histone Deacetylases

This paper introduces the use of mass spectrometry to analyze peptide arrays for applications in profiling enzyme specificity. The strategy is illustrated with arrays containing 361 acetylated peptides to profile the activities of several histone deacetylases (HDACs). The arrays reveal distinct subs...

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Detalhes bibliográficos
Main Authors: Gurard-Levin, Zachary A., Kim, Joohoon, Mrksich, Milan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813191/
https://ncbi.nlm.nih.gov/pubmed/19688789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200900417
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