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Combining Mass Spectrometry and Peptide Arrays to Profile the Specificities of the Histone Deacetylases

This paper introduces the use of mass spectrometry to analyze peptide arrays for applications in profiling enzyme specificity. The strategy is illustrated with arrays containing 361 acetylated peptides to profile the activities of several histone deacetylases (HDACs). The arrays reveal distinct subs...

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Autori principali: Gurard-Levin, Zachary A., Kim, Joohoon, Mrksich, Milan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813191/
https://ncbi.nlm.nih.gov/pubmed/19688789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200900417
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