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Peptide Arrays Identify Isoform-Selective Substrates for Profiling Endogenous Lysine Deacetylase Activity

[Image: see text] This paper reports the development of a class of isoform-selective peptide substrates for measuring endogenous lysine deacetylase (KDAC) activities in cell culture. The peptides were first identified by comparing the substrate specificity profiles of the four KDAC isoforms KDAC2, K...

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Detalhes bibliográficos
Main Authors: Gurard-Levin, Zachary A., Kilian, Kristopher A., Kim, Joohoon, Bähr, Katinka, Mrksich, Milan
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941244/
https://ncbi.nlm.nih.gov/pubmed/20849068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100088g
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