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Control of the Flow Properties of DNA by Topoisomerase II and Its Targeting Inhibitor

The flow properties of DNA are important for understanding cell division and, indirectly, cancer therapy. DNA topology controlling enzymes such as topoisomerase II are thought to play an essential role. We report experiments showing how double-strand passage facilitated by topoisomerase II controls...

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Autori principali: Kundukad, Binu, van der Maarel, Johan R.C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941032/
https://ncbi.nlm.nih.gov/pubmed/20858436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.013
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