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Control of the Flow Properties of DNA by Topoisomerase II and Its Targeting Inhibitor

The flow properties of DNA are important for understanding cell division and, indirectly, cancer therapy. DNA topology controlling enzymes such as topoisomerase II are thought to play an essential role. We report experiments showing how double-strand passage facilitated by topoisomerase II controls...

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Detalhes bibliográficos
Main Authors: Kundukad, Binu, van der Maarel, Johan R.C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941032/
https://ncbi.nlm.nih.gov/pubmed/20858436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.013
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