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Control of the Flow Properties of DNA by Topoisomerase II and Its Targeting Inhibitor

The flow properties of DNA are important for understanding cell division and, indirectly, cancer therapy. DNA topology controlling enzymes such as topoisomerase II are thought to play an essential role. We report experiments showing how double-strand passage facilitated by topoisomerase II controls...

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Hlavní autoři: Kundukad, Binu, van der Maarel, Johan R.C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941032/
https://ncbi.nlm.nih.gov/pubmed/20858436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.013
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