Structural Role of the Conserved Cysteines in the Dimerization of the Viral Transmembrane Oncoprotein E5

The E5 oncoprotein is the major transforming protein of bovine papillomavirus type 1. This 44-residue transmembrane protein can interact with the platelet-derived growth factor receptor β, leading to ligand-independent activation and cell transformation. For productive interaction, E5 needs to dimer...

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Main Authors: Windisch, Dirk, Hoffmann, Silke, Afonin, Sergii, Vollmer, Stefanie, Benamira, Soraya, Langer, Birgid, Bürck, Jochen, Muhle-Goll, Claudia, Ulrich, Anne S.
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2010
主題:
Membrane
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941001/
https://ncbi.nlm.nih.gov/pubmed/20858420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.073
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