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Structural Role of the Conserved Cysteines in the Dimerization of the Viral Transmembrane Oncoprotein E5
The E5 oncoprotein is the major transforming protein of bovine papillomavirus type 1. This 44-residue transmembrane protein can interact with the platelet-derived growth factor receptor β, leading to ligand-independent activation and cell transformation. For productive interaction, E5 needs to dimer...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941001/ https://ncbi.nlm.nih.gov/pubmed/20858420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.073 |
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