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SMC-Specific IGF-1 Overexpression in Apoe(−/−) Mice Does Not Alter Atherosclerotic Plaque Burden but Increases Features of Plaque Stability
OBJECTIVE: Growth factors may play a permissive role in atherosclerosis initiation and progression, in part via their promotion of VSMC accumulation in plaques. However, unstable human plaques often have a relative paucity of VSMC which has been suggested to contribute to plaque rupture and/or erosi...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940990/ https://ncbi.nlm.nih.gov/pubmed/20671230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.210831 |
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