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Low circulating insulin-like growth factor I increases atherosclerosis in ApoE-deficient mice
Some clinical studies have suggested that lower IGF-I levels may be associated with an increased risk of ischemic heart disease. We generated atherosclerosis-prone apolipoprotein E-deficient (ApoE(−/−)) mice with 6T alleles (6T/ApoE(−/−) mice) with a 20% decline in circulating IGF-I and fed these mi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3094094/ https://ncbi.nlm.nih.gov/pubmed/21335474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01081.2010 |
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