Epidermal growth factor receptor variant III mediates head and neck cancer cell invasion via STAT3 activation

Epidermal Growth Factor Receptor (EGFR) is frequently over-expressed in head and neck squamous cell carcinoma (HNSCC) where aberrant signaling downstream of this receptor contributes to tumor growth. EGFR variant III (EGFRvIII) is the most commonly altered form of EGFR and contains a truncated ligan...

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Bibliographische Detailangaben
Hauptverfasser: Suzuki, Shinsuke, Morgan, Sarah E., Thomas, Sufi M., Sen, Malabika, Leeman-Neill, Rebecca J., Kuan, Chien-Tsun, Bigner, Darrell, Gooding, William E., Lai, Stephen Y., Grandis, Jennifer R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940981/
https://ncbi.nlm.nih.gov/pubmed/20622897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.279
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