O(6)-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients

O(6)-Methylguanine DNA methyltransferase (MGMT) is implicated as a major predictive factor for treatment response to alkylating agents including temozolomide (TMZ) of glioblastoma multiforme (GBM) patients. However, whether the MGMT status in GBM patients should be detected at the level of promoter...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Spiegl-Kreinecker, Sabine, Pirker, Christine, Filipits, Martin, Lötsch, Daniela, Buchroithner, Johanna, Pichler, Josef, Silye, Rene, Weis, Serge, Micksche, Michael, Fischer, Johannes, Berger, Walter
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2010
Предметы:
Basic and Translational Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940563/
https://ncbi.nlm.nih.gov/pubmed/20150365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop003
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы