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TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma

BACKGROUND: Meningiomas are mostly benign tumors tending to progress to higher-grade lesions. Mutations in the telomerase reverse transcriptase (TERT) gene promoter are comparably rare in meningioma, but were recently suggested to predict risk of recurrence and progression. Here we have analyzed a c...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Spiegl-Kreinecker, Sabine, Lötsch, Daniela, Neumayer, Katharina, Kastler, Lucia, Gojo, Johannes, Pirker, Christine, Pichler, Josef, Weis, Serge, Kumar, Rajiv, Webersinke, Gerald, Gruber, Andreas, Berger, Walter
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231195/
https://ncbi.nlm.nih.gov/pubmed/30010853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy104
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