TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma

BACKGROUND: Meningiomas are mostly benign tumors tending to progress to higher-grade lesions. Mutations in the telomerase reverse transcriptase (TERT) gene promoter are comparably rare in meningioma, but were recently suggested to predict risk of recurrence and progression. Here we have analyzed a c...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Spiegl-Kreinecker, Sabine, Lötsch, Daniela, Neumayer, Katharina, Kastler, Lucia, Gojo, Johannes, Pirker, Christine, Pichler, Josef, Weis, Serge, Kumar, Rajiv, Webersinke, Gerald, Gruber, Andreas, Berger, Walter
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Basic and Translational Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231195/
https://ncbi.nlm.nih.gov/pubmed/30010853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy104
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