TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma

BACKGROUND: Meningiomas are mostly benign tumors tending to progress to higher-grade lesions. Mutations in the telomerase reverse transcriptase (TERT) gene promoter are comparably rare in meningioma, but were recently suggested to predict risk of recurrence and progression. Here we have analyzed a c...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Spiegl-Kreinecker, Sabine, Lötsch, Daniela, Neumayer, Katharina, Kastler, Lucia, Gojo, Johannes, Pirker, Christine, Pichler, Josef, Weis, Serge, Kumar, Rajiv, Webersinke, Gerald, Gruber, Andreas, Berger, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231195/
https://ncbi.nlm.nih.gov/pubmed/30010853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy104
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