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OS08.1 TERT promoter mutations in Meningiomas drive tumor aggressiveness and cellular immortalization

Introduction: TERT promoter mutations in meningiomas were recently found to be strongly prognostic and associated with risk of recurrence. However, the impact of these genomic alterations on telomere-associated parameters namely TERT mRNA expression, telomerase activity and telomere lengths was not...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Spiegl-Kreinecker, S., Loetsch, Laaber, Neumayer, Pichler, Weis, Webersinke, Gruber, Berger
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463626/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.051
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