P04.24 MUTATIONS OF THE TERT PROMOTER CORRELATE WITH ENHANCED TELOMERASE ACTIVATION AND PREDICT A WORSE PROGNOSIS IN PRIMARY GLIOBLASTOMA PATIENTS

The stabilization of telomeres by upregulation of telomerase is compulsive for indefinite proliferation and cell immortalization therefore representing a main feature of malignant solid tumors, including gliomas. However, the mechanisms responsible for cancer-associated telomerase activation are not...

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Autors principals: Spiegl-Kreinecker, S., Loetsch, D., Laaber, M., Pichler, J., Weis, S., Ghanim, B., Webersinke, G., Olschowski, A., Berger, W.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Poster Presentations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185501/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.156
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