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Testing of VKORC1 and CYP2C9 alleles to guide warfarin dosing: Test Category: Pharmacogenomic (Treatment)

Warfarin is an oral anticoagulant that is widely prescribed to prevent thromboembolic events in persons at increased risk. The optimal dose is difficult to establish because it can vary 10-fold among individuals due to clinical and demographic factors. Testing for variants of the vitamin K epoxide r...

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Bibliographic Details
Main Author: Grossniklaus, Daurice
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940214/
https://ncbi.nlm.nih.gov/pubmed/20877452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1155
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