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The unfolded protein response in melanocytes: activation in response to chemical stressors of the endoplasmic reticulum and tyrosinase misfolding
Accumulation of proteins in the endoplasmic reticulum (ER) triggers the unfolded protein response (UPR), comprising three signaling pathways initiated by Ire1, Perk and Atf6 respectively. UPR activation was compared in chemically stressed murine wildtype melanocytes and mutant melanocytes that retai...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2939946/ https://ncbi.nlm.nih.gov/pubmed/20444203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2010.00718.x |
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