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Vitiligo inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8

Vitiligo is characterized by depigmented skin patches due to loss of epidermal melanocytes. Oxidative stress may play a role in vitiligo onset, while autoimmunity contributes to disease progression. In this study we sought to identify mechanisms that link disease triggers and spreading of lesions. A...

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Detalhes bibliográficos
Main Authors: Toosi, Siavash, Orlow, Seth J., Manga, Prashiela
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443495/
https://ncbi.nlm.nih.gov/pubmed/22696056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.181
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