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Vitiligo inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8

Vitiligo is characterized by depigmented skin patches due to loss of epidermal melanocytes. Oxidative stress may play a role in vitiligo onset, while autoimmunity contributes to disease progression. In this study we sought to identify mechanisms that link disease triggers and spreading of lesions. A...

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Detaylı Bibliyografya
Asıl Yazarlar: Toosi, Siavash, Orlow, Seth J., Manga, Prashiela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443495/
https://ncbi.nlm.nih.gov/pubmed/22696056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.181
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