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The nuclear factor (erythroid-derived 2)-like 2 (NRF2) antioxidant response promotes melanocyte viability and reduces toxicity of the vitiligo-inducing phenol monobenzone

Vitiligo, characterized by progressive melanocyte death, can be initiated by exposure to vitiligo-inducing phenols (VIPs). VIPs generate oxidative stress in melanocytes and activate the master antioxidant regulator NRF2. While NRF2-regulated antioxidants are reported to protect melanocytes from oxid...

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Detalhes bibliográficos
Publicado no:Exp Dermatol
Main Authors: Arowojolu, Omotayo A., Orlow, Seth J., Elbuluk, Nada, Manga, Prashiela
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507766/
https://ncbi.nlm.nih.gov/pubmed/28370349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.13350
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