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Structure and Base Pairing Properties of a Replicable Nonpolar Isostere for Deoxyadenosine
We report the synthesis, structure, and pairing properties in DNA of an isostere for deoxyadenosine which lacks all hydrogen-bonding functionality on the Watson–Crick pairing edge. A deoxyribo-nucleoside derivative of 4-methylbenzimidazole (1), which was recently shown to be inserted into DNA by Kle...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2939748/ https://ncbi.nlm.nih.gov/pubmed/20852720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo9805100 |
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