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Novel Cationic Lipids with Enhanced Gene Delivery and Antimicrobial Activity

Cationic lipids facilitate plasmid delivery, and some cationic sterol-based compounds have antimicrobial activity because of their amphiphilic character. These dual functions are relevant in the context of local ongoing infection during intrapulmonary gene transfer for cystic fibrosis. The transfect...

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מידע ביבליוגרפי
Main Authors: Fein, David E., Bucki, Robert, Byfield, Fitzroy, Leszczynska, Katarzyna, Janmey, Paul A., Diamond, Scott L.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939482/
https://ncbi.nlm.nih.gov/pubmed/20573781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.066670
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