Novel Cationic Lipids with Enhanced Gene Delivery and Antimicrobial Activity

Cationic lipids facilitate plasmid delivery, and some cationic sterol-based compounds have antimicrobial activity because of their amphiphilic character. These dual functions are relevant in the context of local ongoing infection during intrapulmonary gene transfer for cystic fibrosis. The transfect...

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Bibliographic Details
Main Authors: Fein, David E., Bucki, Robert, Byfield, Fitzroy, Leszczynska, Katarzyna, Janmey, Paul A., Diamond, Scott L.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2010
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939482/
https://ncbi.nlm.nih.gov/pubmed/20573781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.066670
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