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Novel Cationic Lipids with Enhanced Gene Delivery and Antimicrobial Activity

Cationic lipids facilitate plasmid delivery, and some cationic sterol-based compounds have antimicrobial activity because of their amphiphilic character. These dual functions are relevant in the context of local ongoing infection during intrapulmonary gene transfer for cystic fibrosis. The transfect...

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Bibliografiske detaljer
Main Authors: Fein, David E., Bucki, Robert, Byfield, Fitzroy, Leszczynska, Katarzyna, Janmey, Paul A., Diamond, Scott L.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939482/
https://ncbi.nlm.nih.gov/pubmed/20573781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.066670
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