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Characterization of the Glycosyltransferase DesVII and Its Auxiliary Partner Protein DesVIII in the Methymycin/Pikromycin Biosynthetic Pathway

The in vitro characterization of the catalytic activity of DesVII, the glycosyltransferase involved in the biosynthesis of the macrolide antibiotics methymycin, neomethymycin, narbomycin, and pikromycin in Streptomyces venezuelae, is described. DesVII is unique among glycosyltransferases in that it...

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Détails bibliographiques
Auteurs principaux: Borisova, Svetlana A., Liu, Hung-wen
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939310/
https://ncbi.nlm.nih.gov/pubmed/20695498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1007657
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