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Characterization of the Glycosyltransferase DesVII and Its Auxiliary Partner Protein DesVIII in the Methymycin/Pikromycin Biosynthetic Pathway

The in vitro characterization of the catalytic activity of DesVII, the glycosyltransferase involved in the biosynthesis of the macrolide antibiotics methymycin, neomethymycin, narbomycin, and pikromycin in Streptomyces venezuelae, is described. DesVII is unique among glycosyltransferases in that it...

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Detalhes bibliográficos
Main Authors: Borisova, Svetlana A., Liu, Hung-wen
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939310/
https://ncbi.nlm.nih.gov/pubmed/20695498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1007657
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