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Characterization of the Glycosyltransferase DesVII and Its Auxiliary Partner Protein DesVIII in the Methymycin/Pikromycin Biosynthetic Pathway

The in vitro characterization of the catalytic activity of DesVII, the glycosyltransferase involved in the biosynthesis of the macrolide antibiotics methymycin, neomethymycin, narbomycin, and pikromycin in Streptomyces venezuelae, is described. DesVII is unique among glycosyltransferases in that it...

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Библиографические подробности
Главные авторы: Borisova, Svetlana A., Liu, Hung-wen
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939310/
https://ncbi.nlm.nih.gov/pubmed/20695498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1007657
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