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Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy

AIM: Tau protein is a prominent component of paired helical filaments in Alzheimer's disease (AD) and other tauopathies. While the abnormal phosphorylation of tau on serine and threonine has been well established in the disease process, its phosphorylation on tyrosine has only recently been des...

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Détails bibliographiques
Auteurs principaux: Bhaskar, Kiran, Hobbs, G. Aaron, Yen, Shu-Hui, Lee, Gloria
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939304/
https://ncbi.nlm.nih.gov/pubmed/20609109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2990.2010.01103.x
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