載入...
Identification of a PRMT5-dependent repressor complex linked to silencing of human fetal globin gene expression
Defining the molecular mechanisms underpinning fetal (γ) globin gene silencing may provide strategies for reactivation of γ-gene expression, a major therapeutic objective in patients with β-thalassemia and sickle cell disease (SCD). We have previously demonstrated that symmetric methylation of histo...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2010
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938845/ https://ncbi.nlm.nih.gov/pubmed/20495075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-251116 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|