Repression of human γ-globin gene expression by a short isoform of the NF-E4 protein is associated with loss of NF-E2 and RNA polymerase II recruitment to the promoter

Binding of the stage selector protein (SSP) to the stage selector element (SSE) in the human γ-globin promoter contributes to the preferential expression of the γ-gene in fetal erythroid cells. The SSP contains the transcription factor CP2 and an erythroid-specific partner, NF-E4. The NF-E4 gene enc...

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Detalhes bibliográficos
Main Authors: Zhao, Quan, Zhou, Wenlai, Rank, Gerhard, Sutton, Rosemary, Wang, Xi, Cumming, Helen, Cerruti, Loretta, Cunningham, John M., Jane, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Red Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895715/
https://ncbi.nlm.nih.gov/pubmed/16263792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2497
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