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piggyBac Transposon/Transposase System to Generate CD19-Specific T Cells for the Treatment of B-Lineage Malignancies

Nonviral integrating vectors can be used for expression of therapeutic genes. piggyBac (PB), a transposon/transposase system, has been used to efficiently generate induced pluripotent stems cells from somatic cells, without genetic alteration. In this paper, we apply PB transposition to express a ch...

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Detalhes bibliográficos
Principais autores: Raja Manuri, Pallavi V., Wilson, Matthew H., Maiti, Sourindra N., Mi, Tiejuan, Singh, Harjeet, Olivares, Simon, Dawson, Margaret J., Huls, Helen, Lee, Dean A., Rao, Pulivarthi H., Kaminski, Joseph M., Nakazawa, Yozo, Gottschalk, Stephen, Kebriaei, Partow, Shpall, Elizabeth J., Champlin, Richard E., Cooper, Laurence J.N.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938363/
https://ncbi.nlm.nih.gov/pubmed/19905893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.114
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