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A hyperactive piggyBac transposase for mammalian applications

DNA transposons have been widely used for transgenesis and insertional mutagenesis in various organisms. Among the transposons active in mammalian cells, the moth-derived transposon piggyBac is most promising with its highly efficient transposition, large cargo capacity, and precise repair of the do...

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Bibliografiske detaljer
Main Authors: Yusa, Kosuke, Zhou, Liqin, Li, Meng Amy, Bradley, Allan, Craig, Nancy L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029773/
https://ncbi.nlm.nih.gov/pubmed/21205896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008322108
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