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Hyperactive piggyBac Gene Transfer in Human Cells and In Vivo
We characterized a recently developed hyperactive piggyBac (pB) transposase enzyme [containing seven mutations (7pB)] for gene transfer in human cells in vitro and to somatic cells in mice in vivo. Despite a protein level expression similar to that of native pB, 7pB significantly increased the gene...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3300075/ https://ncbi.nlm.nih.gov/pubmed/21992617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.138 |
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