A Hyperactive Transposase Promotes Persistent Gene Transfer of a piggyBac DNA Transposon

Nonviral vector systems are used increasingly in gene targeting and gene transfer applications. The piggyBac transposon represents an alternative integrating vector for in vivo gene transfer. We hypothesized that this system could achieve persistent gene transfer to the liver when administered syste...

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Detalhes bibliográficos
Main Authors: Burnight, Erin R, Staber, Janice M, Korsakov, Pavel, Li, Xianghong, Brett, Benjamin T, Scheetz, Todd E, Craig, Nancy L, McCray, Paul B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499692/
https://ncbi.nlm.nih.gov/pubmed/23344650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2012.12
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