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c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development

GATA-3 and c-Myb are core elements of a transcriptionally active complex essential for human Th2 cell development and maintenance. We report herein mechanistic details concerning the role of these transcription factors in human peripheral blood Th2 cell development. Silencing c-Myb in normal human n...

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Hlavní autoři: Nakata, Yuji, Brignier, Anne C., Jin, Shenghao, Shen, Yuan, Rudnick, Stephen I., Sugita, Mayumi, Gewirtz, Alan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938238/
https://ncbi.nlm.nih.gov/pubmed/20484083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-223255
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