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c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis
Mixed-lineage leukemia (MLL) is a proto-oncogene frequently involved in chromosomal translocations associated with acute leukemia. These chromosomal translocations commonly result in MLL fusion proteins that dysregulate transcription. Recent data suggest that the MYB proto-oncogene, which is an impo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810070/ https://ncbi.nlm.nih.gov/pubmed/20093773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38030 |
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