Road blocks on paleogenomes—polymerase extension profiling reveals the frequency of blocking lesions in ancient DNA

Although the last few years have seen great progress in DNA sequence retrieval from fossil specimens, some of the characteristics of ancient DNA remain poorly understood. This is particularly true for blocking lesions, i.e. chemical alterations that cannot be bypassed by DNA polymerases and thus pre...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Heyn, Patricia, Stenzel, Udo, Briggs, Adrian W., Kircher, Martin, Hofreiter, Michael, Meyer, Matthias
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938203/
https://ncbi.nlm.nih.gov/pubmed/20587499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq572
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki