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Direct multiplex sequencing (DMPS)—a novel method for targeted high-throughput sequencing of ancient and highly degraded DNA

Although the emergence of high-throughput sequencing technologies has enabled whole-genome sequencing from extinct organisms, little progress has been made in accelerating targeted sequencing from highly degraded DNA. Here, we present a novel and highly sensitive method for targeted sequencing of an...

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Detalhes bibliográficos
Main Authors: Stiller, Mathias, Knapp, Michael, Stenzel, Udo, Hofreiter, Michael, Meyer, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765274/
https://ncbi.nlm.nih.gov/pubmed/19635845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.095760.109
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