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A2B Adenosine Receptors Protect against Sepsis-Induced Mortality by Dampening Excessive Inflammation

Despite intensive research, efforts to reduce the mortality of septic patients have failed. Adenosine is a potent extracellular signaling molecule, and its levels are elevated in sepsis. Adenosine signals through G-protein–coupled receptors and can regulate the host’s response to sepsis. In this stu...

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Detalhes bibliográficos
Main Authors: Csóka, Balázs, Németh, Zoltán H., Rosenberger, Peter, Eltzschig, Holger K., Spolarics, Zoltán, Pacher, Pál, Selmeczy, Zsolt, Koscsó, Balázs, Himer, Leonóra, Vizi, E. Sylvester, Blackburn, Michael R., Deitch, Edwin A., Haskó, György
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938184/
https://ncbi.nlm.nih.gov/pubmed/20505145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901295
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