Adenosine A(2A) receptor activation inhibits T helper 1 and T helper 2 cell development and effector function

Adenosine is an immunosuppressive nucleoside, and adenosine A(2A) receptors inhibit T-cell activation. We investigated the role of A(2A) receptors in regulating T helper (Th)1- and Th2-cell development and effector function. A(2A)-receptor stimulation suppressed the development of T-cell receptor (T...

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Autors principals: Csóka, Balázs, Himer, Leonóra, Selmeczy, Zsolt, Vizi, E. Sylvester, Pacher, Pál, Ledent, Catherine, Deitch, Edwin A., Spolarics, Zoltán, Németh, Zoltán H., Haskó, György
Format: Artigo
Idioma:Inglês
Publicat: The Federation of American Societies for Experimental Biology 2008
Matèries:
Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2537430/
https://ncbi.nlm.nih.gov/pubmed/18625677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-107458
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