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Adenosine augments interleukin-10 production by microglial cells through an A(2B) adenosine receptor-mediated process
Microglia are activated by pathogen-associated molecular patterns and produce pro-inflammatory cytokines, such as TNF-α, IL-6, and IL-12, and the anti-inflammatory cytokine IL-10. Adenosine is an endogenous purine nucleoside and is a ligand of four G protein-coupled adenosine receptors (ARs), which...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384725/ https://ncbi.nlm.nih.gov/pubmed/22116830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101224 |
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