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Adenosine augments interleukin-10 production by microglial cells through an A(2B) adenosine receptor-mediated process

Microglia are activated by pathogen-associated molecular patterns and produce pro-inflammatory cytokines, such as TNF-α, IL-6, and IL-12, and the anti-inflammatory cytokine IL-10. Adenosine is an endogenous purine nucleoside and is a ligand of four G protein-coupled adenosine receptors (ARs), which...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Koscsó, Balázs, Csóka, Balázs, Selmeczy, Zsolt, Himer, Leonóra, Pacher, Pál, Virág, László, Haskó, György
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384725/
https://ncbi.nlm.nih.gov/pubmed/22116830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101224
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