Adenosine A(2A) receptor activation protects CD4(+) T lymphocytes against activation-induced cell death

Activation-induced cell death (AICD) is initiated by T-cell receptor (TCR) restimulation of already activated and expanded peripheral T cells and is mediated through Fas/Fas ligand (FasL) interactions. Adenosine is a purine nucleoside signaling molecule, and its immunomodulatory effects are mediated...

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Main Authors: Himer, Leonóra, Csóka, Balázs, Selmeczy, Zsolt, Koscsó, Balázs, Pócza, Tímea, Pacher, Pál, Németh, Zoltán H., Deitch, Edwin A., Vizi, E. Sylvester, Cronstein, Bruce N., Haskó, György
Format: Artigo
Jezik:Inglês
Izdano: The Federation of American Societies for Experimental Biology 2010
Teme:
Research Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909295/
https://ncbi.nlm.nih.gov/pubmed/20371613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-155192
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