Influenza A Virus Polymerase: Structural Insights into Replication and Host Adaptation Mechanisms

The heterotrimeric RNA-dependent RNA polymerase of influenza viruses catalyzes RNA replication and transcription activities in infected cell nuclei. The nucleotide polymerization activity is common to both replication and transcription processes, with an additional cap-snatching function being emplo...

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Autores principales: Boivin, Stéphane, Cusack, Stephen, Ruigrok, Rob W. H., Hart, Darren J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937865/
https://ncbi.nlm.nih.gov/pubmed/20538599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R110.117531
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