IL-15 Prevents Apoptosis, Reverses Innate and Adaptive Immune Dysfunction, and Improves Survival in Sepsis

L-15 is a pluripotent antiapoptotic cytokine that signals to cells of both the innate and adaptive immune system and is regarded as a highly promising immunomodulatory agent in cancer therapy. Sepsis is a lethal condition in which apoptosis-induced depletion of immune cells and subsequent immunosupp...

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Autori principali: Inoue, Shigeaki, Unsinger, Jacqueline, Davis, Christopher G., Muenzer, Jared T., Ferguson, Thomas A., Chang, Katherine, Osborne, Dale F., Clark, Andrew T., Coopersmith, Craig M., McDunn, Jonathan E., Hotchkiss, Richard S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937828/
https://ncbi.nlm.nih.gov/pubmed/20026737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902307
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