IL-7 Promotes T Cell Viability, Trafficking, and Functionality and Improves Survival in Sepsis

Sepsis is a highly lethal disorder characterized by widespread apoptosis-induced depletion of immune cells and the development of a profound immunosuppressive state. IL-7 is a potent antiapoptotic cytokine that enhances immune effector cell function and is essential for lymphocyte survival. In this...

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Detalhes bibliográficos
Main Authors: Unsinger, Jacqueline, McGlynn, Margaret, Kasten, Kevin R., Hoekzema, Andrew S., Watanabe, Eizo, Muenzer, Jared T., McDonough, Jacquelyn S., Tschoep, Johannes, Ferguson, Thomas A., McDunn, Jonathan E., Morre, Michel, Hildeman, David A., Caldwell, Charles C., Hotchkiss, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914630/
https://ncbi.nlm.nih.gov/pubmed/20200277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903151
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