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IL-7 Promotes T Cell Viability, Trafficking, and Functionality and Improves Survival in Sepsis

Sepsis is a highly lethal disorder characterized by widespread apoptosis-induced depletion of immune cells and the development of a profound immunosuppressive state. IL-7 is a potent antiapoptotic cytokine that enhances immune effector cell function and is essential for lymphocyte survival. In this...

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Autori principali: Unsinger, Jacqueline, McGlynn, Margaret, Kasten, Kevin R., Hoekzema, Andrew S., Watanabe, Eizo, Muenzer, Jared T., McDonough, Jacquelyn S., Tschoep, Johannes, Ferguson, Thomas A., McDunn, Jonathan E., Morre, Michel, Hildeman, David A., Caldwell, Charles C., Hotchkiss, Richard S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914630/
https://ncbi.nlm.nih.gov/pubmed/20200277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903151
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