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Differential lymphopenia-induced homeostatic proliferation for CD4(+) and CD8(+) T cells following septic injury

Sepsis is a severe, life-threatening infection and a leading cause of death in hospitals. A hallmark of sepsis is the profound apoptosis-induced depletion of lymphocytes generating a lymphopenic environment. As lymphopenia can induce nonantigen-driven homeostatic proliferation (HP), we examined this...

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Detalhes bibliográficos
Main Authors: Unsinger, Jacqueline, Kazama, Hirotaka, McDonough, Jacquelyn S., Hotchkiss, Richard S., Ferguson, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653946/
https://ncbi.nlm.nih.gov/pubmed/19088177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0808491
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