Chronic ethanol induces inhibition of antigen-specific CD8(+) but not CD4(+) immunodominant T cell responses following Listeria monocytogenes inoculation

Chronic ethanol consumption results in immunodeficiency. Previous work with chronic ethanol-fed mice has shown reduced splenic weight and cellularity, including reduced numbers of CD8(+) T cells. However, antigen-specific CD8(+) and CD4(+) T cell responses in chronic ethanol-fed mice have been studi...

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Bibliographische Detailangaben
Hauptverfasser: Gurung, Prajwal, Young, Betty M., Coleman, Ruth A., Wiechert, Susan, Turner, Lucas E., Ray, Nancy B., Waldschmidt, Thomas J., Legge, Kevin L., Cook, Robert T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Society for Leukocyte Biology 2009
Schlagworte:
Pathophysiology, Inflammation, and Host Defense
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626766/
https://ncbi.nlm.nih.gov/pubmed/18820175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0208101
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